Open interactive map →Cheap flights from Santiago to La Serena
Planning a trip from Santiago to La Serena? Current fares start at €19 - a solid entry point for a flight to Chile. Several airlines compete on this route, which helps keep fares relatively stable. Direct and one-stop options are both available - use the booking site to filter by preference. Use the booking button below to check live seats and dates.
For the best prices on this route, aim to book at least 3-4 weeks in advance. Tuesday and Wednesday departures from Santiago tend to be cheaper than Friday or Sunday flights. If €19 is above your budget, set a price alert below and we will email you if this fare drops.
Notify me when prices drop
SkyHopp Recommends
No month-by-month calendar for this route yet.
Alternative routes
Frequently asked questions
How much does a flight from Santiago to La Serena cost?
The cheapest fare currently available from Santiago to La Serena is €19. Prices on this route vary by season, day of week, and how far in advance you book. Click through to compare live availability for your dates before you book. Fares are refreshed regularly as our flight partners publish new availability.
Are there direct flights from Santiago to La Serena?
SkyHopp tracks both direct and connecting flights from Santiago to La Serena. Connecting flights are often priced lower but add travel time due to the layover. Whether a non-stop option exists on specific dates depends on airline schedules - use the "Direct only" filter on the interactive map to see non-stop options, or check the booking site for a full breakdown by stop count.
When is the cheapest time to fly from Santiago to La Serena?
Prices on this route typically dip during shoulder-season months, away from school holidays and public holiday windows. Mid-week departures - particularly Tuesday to Thursday - tend to be cheaper than flights on Fridays and Sundays from Santiago. Set a price alert on this page to watch the fare, or click through to compare live dates. Booking 3-6 weeks in advance generally offers the best balance of price and seat availability on this route.