Open interactive map →Cheap flights from Santiago to Antofagasta
From Santiago, reaching Antofagasta in Chile currently costs from €23. Fares are available from several carriers, with prices shifting week to week. The route includes both direct and connecting options - price and travel time trade off depending on which you choose. €23 is the cheapest fare we currently have.
For the best prices on this route, aim to book at least 3-4 weeks in advance. Tuesday and Wednesday departures from Santiago tend to be cheaper than Friday or Sunday flights. If €23 is above your budget, set a price alert below and we will email you if this fare drops.
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Alternative routes
Other ways to reach Antofagasta
Frequently asked questions
How much does a flight from Santiago to Antofagasta cost?
The cheapest fare currently available from Santiago to Antofagasta is €23. Prices on this route vary by season, day of week, and how far in advance you book. Click through to compare live availability for your dates before you book. Fares are refreshed regularly as our flight partners publish new availability.
Are there direct flights from Santiago to Antofagasta?
SkyHopp tracks both direct and connecting flights from Santiago to Antofagasta. Connecting flights are often priced lower but add travel time due to the layover. Whether a non-stop option exists on specific dates depends on airline schedules - use the "Direct only" filter on the interactive map to see non-stop options, or check the booking site for a full breakdown by stop count.
When is the cheapest time to fly from Santiago to Antofagasta?
Prices on this route typically dip during shoulder-season months, away from school holidays and public holiday windows. Mid-week departures - particularly Tuesday to Thursday - tend to be cheaper than flights on Fridays and Sundays from Santiago. Set a price alert on this page to watch the fare, or click through to compare live dates. Booking 3-6 weeks in advance generally offers the best balance of price and seat availability on this route.