Weekend getaways from Santiago

All cheap flights from Santiago

17 weekend-ready destinations depart from Santiago right now, 14 of them direct. The cheapest fare is €19 to La Serena — all options on this page take under 3 hours each way, leaving enough time for a full Friday-to-Sunday break. Fares are updated regularly; prices shown are the lowest observed this week.

When scanning weekend destinations from Santiago, pay attention to the flight time alongside the fare. The average flight time across options on this page is 2h. A 90-minute flight and a 170-minute flight both qualify as short-haul, but the extra 80 minutes each way makes a real difference on a two-night trip - especially if you are arriving Friday evening and need to make the most of Saturday.

The price calendar on each destination's route page shows how fares vary month by month. Even for weekend trips, picking the right month can matter - fares to the same destination can vary substantially between peak and off-peak periods. If you are planning a few weeks ahead with some flexibility, checking the calendar before committing to a date is worth the time.

Some of the shortest routes from Santiago may also work as single-overnight trips if you prefer to minimise accommodation costs: an early Saturday departure and a Sunday-evening return leaves a full day at the destination. Check the flight schedule before booking - this only works when departure and return times leave enough usable time at the destination.

Best weekend getaways from Santiago right now

Looking for a quick weekend escape from Santiago? These destinations combine short flight times, current low fares, and enough flexibility for a two- or three-day trip. The cheapest option in this list is La Serena from €19.

La Serena
Chile - 1h 9m - Direct
from €19
Calama
Chile - 2h 10m - Direct
from €22
Mendoza
Argentina - 1h 5m - Direct
from €22
Antofagasta
Chile - 2h 2m - Direct
from €23
Concepcion
Chile - 1h 9m - Direct
from €25

Why these destinations?

- Short flight time from the origin airport
- Low current fares compared with nearby destinations
- Practical for a 2-3 day city break or short escape

5 of 5 top options have direct flights available - no connections needed for your weekend.

Booking tip: Saturday-morning departure + Monday-morning return is typically 20-30% cheaper than the popular Friday-evening out, Sunday-evening back pattern.

Prices refresh every 48-72 hours.

Cheapest destinations from Santiago

Weekend getaways from other cities

Frequently asked questions

What's a good weekend trip from Santiago?

Right now the cheapest weekend-ready fare from Santiago is €19 to La Serena, about 1 hours each way. That leaves plenty of time for two full days at your destination even on a Friday-to-Sunday schedule. See the full list above for all 17 options under 3 hours, covering 3 countries.

How many direct flights from Santiago work for a weekend?

14 of the short-haul destinations from Santiago currently have direct fares available. Direct is almost always the right call for a 2-night break — you land fresher, skip the connection stress, and save time on both ends of the trip. If a direct option is even €20 more than a connecting flight, it's usually worth it for a trip this short.

When should I book a weekend flight from Santiago?

4-6 weeks ahead usually gets you the best combination of price and seat availability. Friday-evening departures and Sunday-evening returns are the most popular slots, so they tend to cost more. Comparing a Saturday-morning departure or a Monday return can uncover lower fares on the same routes. Last-minute deals do appear (within 14 days), but availability and price are unpredictable at that stage.

What counts as "short-haul" from Santiago?

We filter to flights under 3 hours one-way. That threshold is based on a practical test: a 3-hour flight allows you to leave Santiago on a Friday evening after work and arrive in time for dinner at your destination — leaving the full Saturday and Sunday free. Flights longer than 3 hours start to eat meaningfully into a 2-night break.