Open interactive map ->Cheap flights from Prague to South America
From Prague (PRG), South America is reachable across 9 destinations. The cheapest fare right now is €346 to Buenos Aires. All prices below are sourced from our flight partners and refreshed as new fares are published.
About this region
- Best for
- culturewildlifeadventurefood
- Typical trip
- 14-21 days
- Typical value months(EU departures)
- AprilMaySeptember
Trip lengths and value months reflect typical patterns for EU-origin departures - individual routes vary.
Popular destinations in South America from Prague
From Prague, travellers most commonly search for flights to Buenos Aires, Santiago, Valencia, Barcelona and Montevideo. Fares across these destinations shift with demand and time of year — earlier bookings and mid-week departures tend to produce lower prices.
Cheapest destinations from Prague
- Buenos AiresArgentinaBookAA20h 45m2 stops€346
- SantiagoChileIberia20h 45m2 stops€395
- ValenciaVenezuelaBookRyanair14h 15m2 stops€536
- BarcelonaVenezuelaBookW414h 35m3 stops€574
- MontevideoUruguayBookW916h 5m2 stops€689
- Rio De JaneiroBrazilBookGQ17h 25m3 stops€762
- AsuncionParaguayBookRyanair15h 45m2 stops€826
- CaracasVenezuelaBookLufthansa13h 5m2 stops€887
- Easter IslandChileBookRyanair23h3 stops€1263
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Frequently asked questions
How many destinations in South America can I fly to from Prague?
SkyHopp currently tracks 9 destinations in South America from Prague (PRG). Prices are refreshed regularly as our flight partners publish new fares. The full list is in the price table above, sorted by cheapest current fare.
What is the cheapest flight from Prague to South America?
Recent fares from Prague to South America have started from €346 to Buenos Aires. Prices change frequently — check the table above for the latest available fares. Booking 4-8 weeks in advance and travelling mid-week typically unlocks the lowest prices on long-haul routes.
Which cities in South America are cheapest to fly to from Prague?
The price table above shows all destinations sorted cheapest first. Prices shift daily, but the top destinations by fare from Prague have recently included Buenos Aires. Clicking through to a destination page shows a 12-month price calendar so you can identify the cheapest month to fly.
When is the best time to fly from Prague to South America?
Shoulder-season months and mid-week departures typically offer the lowest fares on routes from Prague. For South America, the best value windows vary by destination — check the individual route pages for month-by-month price calendars. Booking further in advance is particularly important on long-haul routes, where last-minute fares tend to be significantly higher.