Open interactive map ->Cheap flights from Prague to South America
From Prague (PRG), South America is reachable across 14 destinations. The cheapest recently found fare is €466 to Santiago. All prices below are sourced from our flight partners and refreshed as new fares are published.
About this region
- Best for
- culturewildlifeadventurefood
- Typical trip
- 14-21 days
- Typical value months(EU departures)
- AprilMaySeptember
Trip lengths and value months reflect typical patterns for EU-origin departures - individual routes vary.
Lowest-fare destinations in South America from Prague
Among tracked destinations in South America from Prague, the cheapest currently include Santiago, Salvador, Sao Paulo, Barcelona and Rio de Janeiro.
Cheapest destinations in South America from Prague
Fly from Prague to a specific country in South America
Flights to South America from nearby airports
Other regions from Prague
Weekly deals
Get the cheapest flights from Prague in your inbox
One email per week — best prices, no spam.
Frequently asked questions
How many destinations in South America can I fly to from Prague?
SkyHopp currently tracks 14 destinations in South America from Prague (PRG). The full list is in the price table above, sorted by cheapest tracked fare.
What is the cheapest flight from Prague to South America?
Recent fares from Prague to South America have started from €466 to Santiago. The table above is sorted cheapest first.
Which cities in South America are cheapest to fly to from Prague?
The price table above shows all destinations sorted cheapest first. The lowest observed fares from Prague have recently included Santiago.
Are there direct flights from Prague to South America?
SkyHopp has not observed a non-stop fare from Prague to South America in the current dataset. Tracked fares on this page include at least one stop.