Cheap flights from Frankfurt to South America

From Frankfurt (FRA), South America is reachable across 16 destinations. The cheapest fare right now is €426 to Sao Paulo. All prices below are sourced from our flight partners and refreshed as new fares are published.

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About this region

Best for: culturewildlifeadventurefood
Typical trip: 14-21 days
Typical value months(EU departures): AprilMaySeptember

Trip lengths and value months reflect typical patterns for EU-origin departures - individual routes vary.

Popular destinations in South America from Frankfurt

The most popular destinations in South America from Frankfurt include Sao Paulo, Rio de Janeiro, Valencia, Buenos Aires and La Paz. Prices vary by season, airline, and how far in advance you book. The table below lists all available routes sorted by current fare.

Cheapest destinations in South America from Frankfurt

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Flights to South America from nearby airports

Other regions from Frankfurt

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Frequently asked questions

How many destinations in South America can I fly to from Frankfurt?

SkyHopp currently tracks 16 destinations in South America from Frankfurt (FRA). Prices are refreshed regularly as our flight partners publish new fares. The full list is in the price table above, sorted by cheapest current fare.

What is the cheapest flight from Frankfurt to South America?

Recent fares from Frankfurt to South America have started from €426 to Sao Paulo. Prices change frequently — check the table above for the latest available fares. Booking 4-8 weeks in advance and travelling mid-week typically unlocks the lowest prices on long-haul routes.

Which cities in South America are cheapest to fly to from Frankfurt?

The price table above shows all destinations sorted cheapest first. Prices shift daily, but the top destinations by fare from Frankfurt have recently included Sao Paulo. Clicking through to a destination page shows a 12-month price calendar so you can identify the cheapest month to fly.

When is the best time to fly from Frankfurt to South America?

Shoulder-season months and mid-week departures typically offer the lowest fares on routes from Frankfurt. For South America, the best value windows vary by destination — check the individual route pages for month-by-month price calendars. Booking further in advance is particularly important on long-haul routes, where last-minute fares tend to be significantly higher.