Open interactive map ->Cheap flights from Brussels to South America
15 destinations in South America from Brussels, from €430 to Florianopolis. Fares are refreshed regularly — click any row to compare and continue to booking.
About this region
- Best for
- culturewildlifeadventurefood
- Typical trip
- 14-21 days
- Typical value months(EU departures)
- AprilMaySeptember
Trip lengths and value months reflect typical patterns for EU-origin departures - individual routes vary.
Popular destinations in South America from Brussels
From Brussels, travellers most commonly search for flights to Florianopolis, Sao Paulo, Santiago, Barcelona and Fortaleza. Fares across these destinations shift with demand and time of year — earlier bookings and mid-week departures tend to produce lower prices.
Cheapest destinations from Brussels
- FlorianopolisBrazilBookRyanair16h 5m3 stops€430
- Sao PauloBrazilBookWizz Air17h 50m3 stops€472
- SantiagoChileeasyJet22h 3m3 stops€496
- BarcelonaVenezuelaRyanair13h 40m3 stops€510
- FortalezaBrazilBookRyanair10h 50m1 stop€514
- GoianiaBrazilBookRyanair15h 55m3 stops€521
- Buenos AiresArgentinaBookRyanair18h 15m3 stops€541
- BrasiliaBrazilBookRyanair15h 15m2 stops€565
- JujuyArgentinaBookRyanair18h 25m3 stops€568
- Rio De JaneiroBrazilBookSN14h 35m2 stops€578
- VitoriaBrazilBookSN13h 25m2 stops€583
- BogotaColombiaSN12h 5m1 stop€648
- LimaPeruSN17h 45m2 stops€735
- ParamariboSurinameBookEI12h 55m2 stops€882
- TarijaBoliviaBookLA17h3 stops€1393
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Frequently asked questions
How many destinations in South America can I fly to from Brussels?
SkyHopp currently tracks 15 destinations in South America from Brussels (BRU). Prices are refreshed regularly as our flight partners publish new fares. The full list is in the price table above, sorted by cheapest current fare.
What is the cheapest flight from Brussels to South America?
Recent fares from Brussels to South America have started from €430 to Florianopolis. Prices change frequently — check the table above for the latest available fares. Booking 4-8 weeks in advance and travelling mid-week typically unlocks the lowest prices on long-haul routes.
Which cities in South America are cheapest to fly to from Brussels?
The price table above shows all destinations sorted cheapest first. Prices shift daily, but the top destinations by fare from Brussels have recently included Florianopolis. Clicking through to a destination page shows a 12-month price calendar so you can identify the cheapest month to fly.
When is the best time to fly from Brussels to South America?
Shoulder-season months and mid-week departures typically offer the lowest fares on routes from Brussels. For South America, the best value windows vary by destination — check the individual route pages for month-by-month price calendars. Booking further in advance is particularly important on long-haul routes, where last-minute fares tend to be significantly higher.