Open interactive map ->Cheap flights from Brussels to South America
18 destinations in South America from Brussels, from €396 to Caracas. Fares are refreshed regularly — click any row to compare and continue to booking.
About this region
- Best for
- culturewildlifeadventurefood
- Typical trip
- 14-21 days
- Typical value months(EU departures)
- AprilMaySeptember
Trip lengths and value months reflect typical patterns for EU-origin departures - individual routes vary.
Popular destinations in South America from Brussels
From Brussels, travellers most commonly search for flights to Caracas, Navegantes, Fortaleza, Bogota and Santiago. Fares across these destinations shift with demand and time of year — earlier bookings and mid-week departures tend to produce lower prices.
Cheapest destinations in South America from Brussels
- CaracasVenezuelaBookIberia11h 55m1 stop€396
- NavegantesBrazilBookRyanair14h 25m2 stops€457
- FortalezaBrazilBookIberia10h 50m1 stop€470
- BogotaColombiaIberia13h 5m1 stop€484
- SantiagoChileVueling22h 20m3 stops€513
- Buenos AiresArgentinaBookQS23h 45m3 stops€514
- LimaPeruRyanair17h 55m3 stops€527
- GoianiaBrazilBookRyanair16h 10m3 stops€531
- MaringaBrazilBookRyanair15h 30m3 stops€550
- ValenciaVenezuelaBookVueling14h 45m3 stops€552
- FlorianopolisBrazilBookRyanair16h 5m3 stops€552
- MedellinColombiaBookRyanair15h 31m3 stops€581
- CartagenaColombiaBookRyanair14h 30m2 stops€601
- ArmeniaColombiaBookUX14h 45m3 stops€616
- BrasiliaBrazilBookRyanair15h 15m3 stops€624
- Sao PauloBrazilBookRyanair15h 35m3 stops€640
- Rio de JaneiroBrazilBookRyanair14h 10m2 stops€781
- San Carlos de BarilocheArgentinaBookSN18h2 stops€898
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Frequently asked questions
How many destinations in South America can I fly to from Brussels?
SkyHopp currently tracks 18 destinations in South America from Brussels (BRU). Prices are refreshed regularly as our flight partners publish new fares. The full list is in the price table above, sorted by cheapest current fare.
What is the cheapest flight from Brussels to South America?
Recent fares from Brussels to South America have started from €396 to Caracas. Prices change frequently — check the table above for the latest available fares. Booking 4-8 weeks in advance and travelling mid-week typically unlocks the lowest prices on long-haul routes.
Which cities in South America are cheapest to fly to from Brussels?
The price table above shows all destinations sorted cheapest first. Prices shift daily, but the top destinations by fare from Brussels have recently included Caracas. Clicking through to a destination page shows a 12-month price calendar so you can identify the cheapest month to fly.
When is the best time to fly from Brussels to South America?
Shoulder-season months and mid-week departures typically offer the lowest fares on routes from Brussels. For South America, the best value windows vary by destination — check the individual route pages for month-by-month price calendars. Booking further in advance is particularly important on long-haul routes, where last-minute fares tend to be significantly higher.